Davis Polk advised Charles River Laboratories International, Inc. in connection with its Rule 144A/Regulation S offering of $500 million aggregate principal amount of 4.250% senior notes due 2028. The notes are guaranteed by certain of Charles River’s U.S. subsidiaries that are guarantors under its revolving credit facility.

Charles River is a Wilmington, Massachusetts-based global provider of research models and associated services and of preclinical drug development services. The company provides services to assist pharmaceutical and biotechnology companies, government agencies and leading academic institutions worldwide with enhancing their research and drug development efforts and employs over 14,000 employees worldwide.

The Davis Polk capital markets team included partner Richard D. Truesdell Jr., counsel Jeffrey S. Ramsay and associate Cameron Adamson. The tax team included partner Michael Mollerus and associate Shay Moyal. Counsel David A. Zilberberg and associate Michael Comstock provided environmental advice. Partner Frank J. Azzopardi and associate Jay Frankel provided intellectual property and technology advice. Counsel Gregory D. Hughes provided executive compensation advice. Members of the Davis Polk team are based in the New York and Northern California offices.